ABSTRACT
Purpose@#To study effect of San Gen talkh medicine and San Gen granule medicine, on healthy rats immune system@*Method@#In this study 32 male healthy Wistar rats were randomly divided into normal group, low dose group of San Gen talkh (SGTLD), high dose group of San gen talkh (SGTHD) and group of San Gen granule (SGG). In normal group rats were administrated 0.2m l/kg saline solution, in San gen talkh groups rats with low dose and high dose were administrated 0.85g/kg, 1.70g/kg San Gen talkh respectively and in San gen granule medicine groups rats 1.3 g/kg San gen granule medicine, once daily for 42 day. By Elisa method measured IL-10, IL-12, IL-17, IFN-γ and TGF-β in blood plasma and spleen tissue of rat.@*Result@#In this experimental result, there was no significantly difference all measured cytokine of blood plasm (P>0.05) between healthy group and all medicine group. In spleen tissue, there was significantly increased IFN-γ (P<0.05) and TGF-β (P<0.05) in SGTHD group and was significantly increased IFN-γ (PO.05), IL-10 (P<0.01)and TGF-β (PO.001) in SGG group compared with normal group.@*Conclusion@#High doses San Gen talkh medicine and San Gen granule medicine can support cellular immune system, humoral immune system on healthy rats.
ABSTRACT
Background@#Trogopterus xanthipes Milne-Edwards (Hadan hailmal) is defecation of Olbo mouse with red and yellow foot in Olbo mouse family. Trogopterus xanthipes Milne-Edwards has bitter and little sweety flavor and cool and sharp quality and it has effects such as to remove hot, to stop pain and to to make urinate etc.@*Purpose@#To summarize chemical compounds, pharmacological effects, clinical usage and ancient source notes of Trogopterus xanthipes Milne-Edwards. @*Method@#Вy analys method to analyzed research articlest and ancient source of Trogopterus xanthipes Milne-Edwards in China Biological Medical Digest Data-base, Chinese Journals Full Text Data-base and ancient sources of Mongolian traditional medicine.@*Results and Conclusions@#Trogopterus xanthipes Milne-Edwards is produced juice from gold, silver, copper, iron, lead and tin on cliff during 4 to 6 months and otherwise Trogopterus xanthipes Milne-Edwards is called defecation of olbo mouse. It has many activity chemical compounds, such as nitrogen compound, volatile compound, Triterpenoid, fatty acid, flavone, and microelement and has many pharmacological effects such as anti gastric ulcer, anti inflammation, anti oxidant, anti cerebral ischemic injury, anti cytotoxicity and to improve immunology. In Mongolian traditional medicine, Trogopterus xanthipes Milne-Edwards mainly used to treat hot disease of stomach, liver and kidney, synovial disease, gout and rheumatism etc with single medicine and compound recipe ingredients of Trogopterus xanthipes Milne-Edwards. In Chinese medicine used to treat disease of digestive system and to stop pain etc.